Evidence map›Paper›PMID 41925744›Full record

ArticleActa neurochirurgica2026

Fixed-wing air transport of patients with spinal pathologies: a scoping review of current evidence and future research priorities.

Ashviniy Thamilmaran, Zak Hodgson, Konstantinos Peramatzis, Maria Karampouga, Mark Jarratt, Eleni Tsianaka, Insa K Janssen, Anastasia Tasiou, Nese Keser, Mary Murphy

Abstract readScoping Review
In one paragraph

Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashviniy ThamilmaranUniversity College London Medical School, London, UK. ashviniy.thamilmaran.18@ucl.ac.uk.
Zak HodgsonSchool of Medicine, University of Leeds, Leeds, UK.
Konstantinos PeramatzisDepartment of Aviation Engineering, School of Aviation, Australian University, Safat, Kuwait.
Maria KarampougaDepartment of Neurosurgery, Nicosia General Hospital, Nicosia, Cyprus.
Mark JarrattSpinal Injuries Association, Health and Care Quality Team, Milton Keynes, UK.
Eleni TsianakaDepartment of Neurosurgery & Quality Department, Kuwait Hospital, Sabah Al Salem, Kuwait.
Insa K JanssenDepartment of Neurosurgery, Hôpitaux Universitaires de Genève, Geneva, Switzerland.
Anastasia TasiouDepartment of Neurosurgery, University Hospital of Larissa, Larissa, Greece.
Nese KeserDepartment of Neurosurgery, Hamidiye Faculty of Medicine, University of Health Sciences, Istanbul, Turkey.
Mary MurphyDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRapid transportation of neurosurgical patients, particularly those with acute spinal trauma, is critical due to the direct association between total prehospital time and mortality. While existing aeromedical guidelines focus primarily on helicopter (rotor-wing) transport, there is limited evidence consolidating the effects of fixed-wing aircraft transport, which exposes patients to unique physiological stressors due to higher operational altitudes.

methodsUsing a recognised framework for scoping reviews, a European-based research team conducted biweekly discussions to ensure a comprehensive approach. This scoping review utilized a four-phase framework: identification, screening, data extraction, and contextualisation. A systematic literature search via OVID databases up to September 19, 2024, and manual searches of 15 journals identified studies involving fixed-wing aircraft transport for spinal pathology patients, excluding helicopter or animal studies. Additionally, a panel of experts in neurosurgery and aviation reflected on their experiences and transferable lessons.

results12 studies were included, covering 105 spinal injury cases and 1 spinal tuberculosis case. Key physiological factors unique to fixed-wing transport include reduced atmospheric pressure, low humidity, extended transport duration, smoother acceleration/deceleration, and better medical accessibility compared to rotor-wing transport. Recommendations from the literature and expert experiences emphasise respiratory stability, humidification, oxygen supplementation, pressure injury prevention, bowel/bladder management, airway cuff pressure management, and venous thromboembolism prophylaxis.

conclusionThere is an urgent need for evidence-based recommendations tailored to fixed-wing transportation of spinal pathology patients, emphasizing altitude-induced physiological changes to optimize patient safety. Further targeted research is essential to develop comprehensive clinical protocols.

Indexed as

Air AmbulancesSpinal Cord InjuriesSpinal InjuriesTransportation of PatientsAircraftHumansAeromedical evacuationAerospace medicineAltitude physiologyFixed-wing air transportSpinal cord injurySpinal trauma

Identifiers

PMID41925744
PMCPMC13053554

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