Evidence map›Paper›PMID 41925740›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2026

Pulsed electric field and radiofrequency ablation for paroxysmal supraventricular tachycardia: a propensity score-matched comparison (PFA-SVT study).

Fanghui Li, Xianjin Hu, Zexi Li, Wenjie Li, Bangjiaxin Ren, Yilin Wang, Huan Ren, Aobo Gong, Ying Cao, Yifan Zhou and 1 more

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Fanghui Li *Department of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.ORCID http://orcid.org/0000-0001-6580-3726
Xianjin Hu *Department of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Zexi LiDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Wenjie LiDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Bangjiaxin RenDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Yilin WangDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Huan RenSichuan Jinjiang Electronic Science and Technology Co., Ltd, Chengdu, China.
Aobo GongDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Ying CaoDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Yifan ZhouDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China.
Rui ZengDepartment of Cardiology, West China Hospital of Sichuan University, 37 Guoxue Road, Chengdu, 610041, Sichuan, China. zengrui_0524@126.com.

Funding

Sichuan Province Science and Technology Support Program 2024YFFK0046Sichuan Province Science and Technology Support Program 2026NSFSC1723West China Hospital, Sichuan University 2023HXFH002
6 · The paper itself

Abstract

backgroundPreliminary studies have demonstrated the feasibility of pulsed field ablation (PFA) for the treatment of paroxysmal supraventricular tachycardia (PSVT); however, direct comparative data between PFA and radiofrequency ablation (RFA) with longer-term follow-up are lacking.

objectiveThis study aimed to compare the safety and efficacy profiles of PFA and RFA in PSVT treatment through propensity score matching over a 12-month follow-up period.

methodsThis multicenter prospective study enrolled 621 consecutive patients with PSVT who underwent catheter ablation with PFA (n = 212) or RFA (n = 409) across 8 centers in China. Propensity score matching was performed separately for atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular reentrant tachycardia (AVRT) patients, yielding 107 and 67 matched pairs. The primary and secondary end points were acute ablation and 12-month follow-up success rates, respectively.

resultsThe acute procedural success rate was 100% for both modalities in all matched patients. The 12-month success rates were comparable between the PFA and RFA groups for both AVNRT (97.2% vs. 96.3%, P = 0.701) and AVRT (92.5% vs. 89.6%, P = 0.545). In the AVNRT cohort, all PFA recurrences were observed between 6 and 12 months. Although PFA required more ablation applications (AVNRT: 11.5 vs. 9.0, P < 0.001; AVRT: 15.5 vs. 7.0, P < 0.001), the overall procedure time remained comparable to that of RFA. Transient first-degree AV block was observed in one patient per group in the matched AVNRT cohort and in one RFA-treated patient in the matched AVRT cohort. All patients resolved spontaneously without permanent complications.

conclusionsPFA demonstrated safety and efficacy outcomes comparable to those of RFA, supporting its potential role as an alternative therapeutic option for PSVT management. These findings should be considered hypothesis-generating, and further large-scale randomized trials with longer follow-up and different PFA systems are required for confirmation.

Indexed as

Atrioventricular nodal reentryAtrioventricular reentryParoxysmal supraventricular tachycardiaPropensity score matchingPulsed field ablationRadiofrequency ablation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.