ArticlePrenatal diagnosis2026
Prenatal Magnetic Resonance Imaging Assessment of Fetal Airway Dimensions: Establishing an Anthropometric Database.
Article in Prenatal diagnosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
objectiveFetal airway anomalies can severely impair breathing at birth, potentially causing brain injury or death. Thus, early prenatal diagnosis is essential. While MRI is the most effective imaging modality for evaluating fetal airways, normative MRI data remain scarce.
methodThis retrospective study analyzed fetal MRIs performed at a tertiary-care center between January 2, 2018, and October 11, 2023. Measurements of the trachea and pharynx-including diameters, lengths, and volumes-were collected from axial, sagittal, and coronal slices. Statistical tests included ANOVA, t-test, Wilcoxon, chi-square, and Fisher's exact tests, with significance set at p ≤ 0.05.
resultsMRI data from 278 fetuses-either healthy or with non-airway-affecting anomalies-were analyzed. Airway dimensions significantly increased with gestational age. Tracheal axial diameter ranged from 1.70 to 2.00 mm (p = 0.001), coronal diameter from 2.20 to 3.10 mm (p = 0.001), and sagittal length from 33.1 to 35.9 mm (p = 0.003) between the fifth-sixth and ninth gestational months. Head position influenced pharyngeal but not tracheal measurements.
conclusionThis study provides the first MRI-based normative data for fetal airways, offering valuable reference values for prenatal assessment. MRI proves effective in monitoring airway development and planning neonatal respiratory management.
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