Evidence map›Paper›PMID 41925649›Full record

ArticleJACC. Case reports2026

Two-Staged Transcatheter Aortic Valve Replacement in Severely Calcified Sinotubular Junction.

Shivani Bhat, Chase J Ellingson, Jyotpal Singh, Ure Eziyi, Danielle Dressler, Jeffrey Booker, John G Webb, Payam Dehghani

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shivani BhatPrairie Vascular Research Inc, Regina, Canada; College of Medicine, University of Saskatchewan, Regina, Canada; Saskatchewan Health Authority (SHA), Saskatoon, Canada.
Chase J EllingsonPrairie Vascular Research Inc, Regina, Canada; College of Medicine, University of Saskatchewan, Regina, Canada.
Jyotpal SinghPrairie Vascular Research Inc, Regina, Canada; Saskatchewan Health Authority (SHA), Saskatoon, Canada.
Ure EziyiPrairie Vascular Research Inc, Regina, Canada; College of Medicine, University of Saskatchewan, Regina, Canada; Saskatchewan Health Authority (SHA), Saskatoon, Canada.
Danielle DresslerCollege of Medicine, University of Saskatchewan, Regina, Canada; Saskatchewan Health Authority (SHA), Saskatoon, Canada; Prairie Skies Medical Imaging, Regina, Canada.
Jeffrey BookerPrairie Vascular Research Inc, Regina, Canada; College of Medicine, University of Saskatchewan, Regina, Canada; Saskatchewan Health Authority (SHA), Saskatoon, Canada.
John G WebbCenter for Heart Valve Innovation, University of British Columbia, Vancouver, Canada.
Payam DehghaniPrairie Vascular Research Inc, Regina, Canada; College of Medicine, University of Saskatchewan, Regina, Canada; Saskatchewan Health Authority (SHA), Saskatoon, Canada. Electronic address: payam.dehghani@saskhealthauthority.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSevere sinotubular junction (STJ) calcification presents important challenges during transcatheter aortic valve implantation, including risk of aortic dissection or aortic root rupture and valve malposition. We describe a straightforward and reproducible two-stage balloon inflation technique with a balloon-expandable SAPIEN 3 valve to optimize precision and procedural safety in this difficult setting. TECHNIQUE: Step 1: Initial balloon inflation at 2 mL less than nominal volume to secure annular anchoring and limit radial force on the calcified STJ. Step 2: Balloon advanced 1-2 mm under fluoroscopy toward the inflow and inflated to the full nominal volume, completing valve deployment. PITFALLS: Inadequate anchoring may cause migration or embolization, underestimation of calcification can compromise expansion, and balloon overinflation may cause root injury.

conclusionThis staged inflation method anchors the valve, minimizes STJ stress, and provides a simple, reproducible strategy that may improve safety in anatomically complex patients.

Indexed as

aortic valveimagingvalve replacement

Identifiers

PMID41925649
PMCPMC13154075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.