Evidence map›Paper›PMID 41925306›Full record

ArticleChemical research in toxicology2026

Arsenic and Cadmium in Cigar Fillers: A Comparative Study within Cigar Types and with Cigarettes.

Mona Shrestha, R Steven Pappas, Nathalie Gonzalez-Jimenez, Naudia Gray, Clifford H Watson, Liza Valentín-Blasini, Munkhzul Otgonsuren, Kenneth M Taylor, Matthew Hassink

Abstract readComparative Study
In one paragraph

Article in Chemical research in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mona ShresthaOffice of Science, Center for Tobacco Products, Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.ORCID 0009-0003-0611-1473
R Steven PappasTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States.ORCID 0000-0002-8684-2879
Nathalie Gonzalez-JimenezTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States.
Naudia GrayTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States.ORCID 0000-0002-6594-3267
Clifford H WatsonTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States.
Liza Valentín-BlasiniTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States.
Munkhzul OtgonsurenOffice of Science, Center for Tobacco Products, Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.
Kenneth M TaylorOffice of Applied Science, Center for Veterinary Medicine, Food and Drug Administration, Laurel, Maryland 20708, United States.ORCID 0000-0002-5130-5758
Matthew HassinkOffice of Science, Center for Tobacco Products, Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland 20993, United States.ORCID 0009-0008-1627-8011

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigar use has increased since the early 1990s; however, there is limited research on the quantity of carcinogenic metals such as arsenic and cadmium in cigars in general and especially within each of the numerous cigar types. The levels of cadmium and arsenic present in the tobacco filler of 67 little cigars, 21 cigarillos, and 19 large cigars were quantitatively analyzed using "triple-quad" inductively coupled plasma mass spectrometry (ICP-MS). Median arsenic concentrations in little cigars, cigarillos (medium-sized cigars), and large cigars were 0.219, 0.224, and 0.193 μg/g, respectively. For cadmium, the median concentration in little cigars was 1.21 μg/g while both cigarillos and large cigars had median cadmium concentrations of 1.32 μg/g. Median arsenic and cadmium concentrations on a per gram basis differed significantly across cigar types (Kruskal-Wallis, both

Indexed as

ArsenicCadmiumTobacco ProductsMass SpectrometryArsenicCadmium

Identifiers

PMID41925306
PMCPMC13100984

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.