Evidence map›Paper›PMID 41925148›Full record

ArticleACS biomaterials science & engineering2026

Synergistic Low-Intensity Pulsed Ultrasound-Activated Vancomycin-Loaded Microbubbles for MRSA Biofilm Eradication and Bone Regeneration in Periprosthetic Joint Infection.

Wenbo Mu, Liqin Yao, Fei Wang, Youcai Ma, Kaisaierjiang Kadier, Junping Hu, Li Cao, Jianhua Yang

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Wenbo MuDepartment of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Liqin YaoDepartment of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Fei WangDepartment of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Youcai MaDepartment of Sports Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Kaisaierjiang KadierDepartment of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Junping HuDepartment of Pharmacognosy, School of Pharmacy, Xinjiang Medical University, Urumqi, Xinjiang 830017, China.
Li CaoDepartment of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Jianhua YangDepartment of Pharmacy, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China.ORCID 0009-0003-1989-9079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periprosthetic joint infection (PJI), sustained by antibiotic-tolerant biofilms, hinders infection control and impairs bone healing. To address this, we developed a dual-action strategy combining low-intensity pulsed ultrasound (LIPUS) with vancomycin-loaded microbubbles (MBs@V) designed to concurrently eliminate methicillin-resistant

Indexed as

Anti-Bacterial AgentsBiofilmsBone RegenerationMethicillin-Resistant Staphylococcus aureusMicrobubblesProsthesis-Related InfectionsStaphylococcal InfectionsUltrasonic WavesVancomycinAnimalsRatsRats, Sprague-DawleyAnti-Bacterial AgentsVancomycinbiofilmbone regenerationlow-intensity pulsed ultrasoundmethicillin-resistant Staphylococcus aureusvancomycin-loaded microbubbles

Identifiers

PMID41925148
PMCPMC13080767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.