Evidence map›Paper›PMID 41924750›Full record

SynthesisFrontiers in medicine2026

Qingke Pingchuan granules as adjuvant therapy for acute exacerbation of chronic obstructive pulmonary disease, acute exacerbation asthma, and acute bronchitis: a systematic review and meta-analysis.

Jiaxiang Li, Jianan He, Ming Gao, Zhiyue Yu, Xiaowen Wu, Limei Geng, Huiting Hu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaxiang Li *Graduate School, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Jianan He *Graduate School, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Ming GaoGraduate School, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Zhiyue YuGraduate School, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Xiaowen WuGraduate School, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Limei GengDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Hebei University of Traditional Chinese Medicine, Shijiazhuang, Hebei, China.
Huiting HuDepartment of Respiratory and Critical Care Medicine, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD), Acute Exacerbation of Asthma(AEA), and acute bronchitis (AB) are known as the common acute airway inflammatory illnesses. This study seeks to systematically assess the effective rate and safety of Qingke Pingchuan Granules (QKPC) in treating these three illnesses in order to give evidence-based recommendations for therapeutic practice. Methods: Web of Science, PubMed, Cochrane Library, Elsevier ScienceDirect, CNKI, Wanfang Data, and VIP databases were all thoroughly scoured between their creation and November 2025. Leveraging the Cochrane Risk of Bias tool, two reviewers independently sifted through the reports, retrieved study data, and assessed the methodological rigor. RevMan 5.4 and Stata 17.0 software were used for statistical analyses, and effect sizes were reported as RR or MD with 95% CIs. The Cochrane Q test and the I Results: 21 RCTs with 2087 individuals were incorporated into this study. The findings demonstrated that QKPC in conjunction with conventional treatment considerably improved clinical outcomes, including overall response rate, FEV₁%, and FVC, as compared to conventional Western medicine alone. Additionally, it decreased the inflammatory factor (CRP). QKPC significantly improved the CAT score, mMRC score, 6MWT distance, and PaO₂ for AECOPD-specific outcomes (all Conclusion: In patients with AECOPD, AEA, and AB, QKPC in conjunction with traditional Western medicine treatment can dramatically enhance clinical efficacy, lung function, and inflammatory status without raising the risk of adverse reactions. For these acute airway inflammatory illnesses, it is a safe and effective adjuvant therapy alternative that indicated to significantly improve symptoms, lung function, and quality of life in individuals with AECOPD. Systematic review registration: Unique Identifier (CRD420251229191), (https://www.crd.york.ac.uk/PROSPERO/view/CRD420251229191).

Indexed as

acute asthma exacerbationacute bronchitisacute exacerbation of chronic obstructive pulmonary diseasemeta-analysisQingke Pingchuan granules

Identifiers

PMID41924750
PMCPMC13036208

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.