ArticleFrontiers in oncology2026
BRAF class II-III mutations in NSCLC: a single center experience.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Currently, there is no consensus on the optimal treatment sequence for NSCLC patients with class II-III Materials and methods: This is an observational, single centre case series of 9 patients collected in a Cancer Institute in Italy diagnosed with NSCLC with a Results: The most common mutation was BRAF G469 (class IIb), observed in 4 of 9 patients. Median age was 76 years. Only three patients received dabrafenib and trametinib for longer than one month, achieving stable disease as the best response. Among these patients, median progression-free survival was 7.5 months and median overall survival was 18.7 months. Across the entire cohort, median overall survival was 16.6 months. Independently of the prior treatment received, only one patient experienced grade 3 treatment-related toxicity. Conclusions: This case series highlights the clinical heterogeneity and poor prognosis of NSCLC patients with
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.