Evidence map›Paper›PMID 41924577›Full record

ArticleChemical science2026

Crosslinker nanocarrier-based intratumoral delivery for protein complex mapping in mitochondria of live tumor-bearing mice.

Yuwan Chen, Wenxin Fu, Baofu Ma, Xinwei Li, Wen Zhou, Zhen Liang, Kaiguang Yang, Lihua Zhang, Yukui Zhang

Abstract read
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuwan ChenState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.
Wenxin FuState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.
Baofu MaState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.
Xinwei LiState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.
Wen ZhouState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.
Zhen LiangState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.
Kaiguang YangState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.ORCID https://orcid.org/0000-0001-9544-2714
Lihua ZhangState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.ORCID https://orcid.org/0000-0003-2543-1547
Yukui ZhangState Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China lihuazhang@dicp.ac.cn yangkaiguang@dicp.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria, the powerhouses of the cell, are central to tumor initiation and growth, yet their protein interactions in living tumors remain poorly understood. Although crosslinking mass spectrometry (XL-MS) has revealed protein conformations and interactions in cultured cells and isolated tissues, its

Identifiers

PMID41924577
PMCPMC13037642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.