ArticleFrontiers in microbiology2026
Environmental stress shapes persistence-like phenotypes and genomic changes in
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Enterobacterales, including Methods: Clinical and environmental Results: Strains exhibited variation in growth kinetics under different stress conditions compared to controls. Temperature, pH, and osmotic stress each affected bacterial growth to varying degrees. Heat stress in particular promoted increased persister-like cell formation in Discussion: This exploratory study suggests that environmental stress drives both phenotypic and genotypic changes, and that these enhance subsequent survival upon challenge with antibiotics. These adaptive responses may contribute to antibiotic tolerance and chronic infection, emphasizing the need for therapeutic strategies targeting stress response pathways.
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