Evidence map›Paper›PMID 41924425›Full record

ReviewFrontiers in cellular and infection microbiology2026

Immune evasion of multidrug-resistant bacteria: insights from lung innate immune cells and targeted therapies.

Yingfei Xu, Yongheng Gao, Yujuan Li, Lei Pan

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingfei Xu *Department of Pulmonary and Critical Care Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yongheng Gao *Department of Pulmonary and Critical Care Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yujuan LiDepartment of Pulmonary and Critical Care Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Lei PanDepartment of Pulmonary and Critical Care Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pneumonia is a common acute infectious disease affecting the lower respiratory tract. Innate immune cells within the lungs play a crucial role in the onset and progression of pneumonia. Various multidrug-resistant bacteria have evolved multiple strategies to evade innate immunity, posing significant challenges to the treatment of pneumonia. This review primarily explores the major innate immune cells in the lungs and their functions, the immune evasion mechanisms of common multidrug-resistant bacteria, and the latest research advances in targeted innate immunity-based anti-infective therapies. This review synthesizes recent advances in the interaction between the innate immune system of the lungs and multidrug-resistant bacteria. It systematically categorizes and compares the immune evasion mechanisms of multidrug-resistant bacteria across four core pathways. This aims to provide novel insights for treating pulmonary infections caused by these multidrug-resistant pathogens.

Indexed as

BacteriaDrug Resistance, Multiple, BacterialImmune EvasionImmunity, InnateLungPneumonia, BacterialAnimalsAnti-Bacterial AgentsHost-Directed TherapyHost-Pathogen InteractionsHumansAnti-Bacterial Agentsimmune escapeimmunotherapyinnate immune cellsmultidrug-resistant bacteriapneumonia

Identifiers

PMID41924425
PMCPMC13036122

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.