Evidence map›Paper›PMID 41924410›Full record

ArticleCureus2026

Incarcerated Ventral Hernia Requiring Emergent Repair in an Adult With Down Syndrome: Diagnostic and Postoperative Challenges in an Underrepresented Population.

Zuhayr Khan, Mahsum Jafri, Constantino G Lambroussis

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zuhayr KhanGeneral Medicine, Lake Erie College of Osteopathic Medicine, Elmira, USA.
Mahsum JafriInternal Medicine, Lake Erie College of Osteopathic Medicine, Elmira, USA.
Constantino G LambroussisOsteopathic Medicine/Family Medicine, Lake Erie College of Osteopathic Medicine, Elmira, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The manifestation of ventral hernias is quite common, with an increased risk of progressing to incarceration/strangulation, which imposes the need for emergent surgery. Patients with Down syndrome (DS) present unique anatomical, physiological, and neurodevelopmental characteristics that may complicate diagnosis and postoperative management. In general, DS has been well studied for perioperative risk primarily with pediatric and cardiac populations, yet emergency general surgical outcomes in adults remain poorly studied. In our case report, a 59-year-old woman with DS and Alzheimer's disease underwent emergent robotic ventral hernia repair for an incarcerated ventral hernia. Her postoperative course was complicated by several features, including obstipation, urinary retention with bilateral hydronephrosis, and the development of bilateral segmental and subsegmental pulmonary emboli on postoperative day four. Interventions for these complications, such as a Foley catheter insertion for urinary retention, led to additional complications. Diagnosis and management were primarily guided by physical examination and cross-sectional imaging, given the patient's limited ability to provide a reliable clinical history. Our case report highlights the challenges of standard postoperative care in adults with DS and also stresses the importance of personalized monitoring, diagnostic imaging, and multidisciplinary approaches, especially for individuals with complex disease processes.

Indexed as

alzheimer's diseasedown syndromeherniaincarcerated ventral herniastrangulated ventral hernia

Identifiers

PMID41924410
PMCPMC13035861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.