Evidence map›Paper›PMID 41924409›Full record

ArticleCureus2026

Intravenous Immunoglobulin for Refractory Streptococcal Toxic Shock Syndrome With Purpura Fulminans: A Case Report and Literature Review.

Rakshit Shetty, Shyam Kiran Gandam Venkata, Sai Sruthi Bhuram, Sudeep Chakravarthy Bhuram, Mahi Chanpura

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rakshit ShettyDepartment of Critical Care Medicine, Springfield Clinic, Springfield, USA.
Shyam Kiran Gandam VenkataDepartment of Critical Care Medicine, Springfield Clinic, Springfield, USA.
Sai Sruthi BhuramDepartment of Critical Care Medicine, Springfield Clinic, Springfield, USA.
Sudeep Chakravarthy BhuramDepartment of Critical Care Medicine, Springfield Clinic, Springfield, USA.
Mahi ChanpuraDepartment of Critical Care Medicine, Springfield Clinic, Springfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcal toxic shock syndrome (STSS) is a rare but life-threatening condition characterized by rapid progression to septic shock and multiorgan dysfunction driven by toxin-mediated immune activation. We report the case of a previously healthy 39-year-old man who presented with acute encephalopathy and rapidly deteriorated into refractory septic shock requiring mechanical ventilation, maximal vasopressor support, and continuous renal replacement therapy. Blood cultures identified

Indexed as

critical illnessimmunomodulatory therapyintravenous immunoglobulininvasive group a streptococcal infectionmultiorgan failurepurpura fulminansrefractory septic shockstreptococcal toxic shock syndromestreptococcus pyogenestoxin-mediated shock

Identifiers

PMID41924409
PMCPMC13036273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.