ArticleInternational journal of ophthalmology2026
Ocular surface characteristics and dry eye symptoms in primary biliary cholangitis patients complicated with seasonal allergic conjunctivitis.
Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
aimTo evaluate ocular surface characteristics and dry eye symptoms in primary biliary cholangitis (PBC) patients with seasonal allergic conjunctivitis (SAC).
methodsThis retrospective case-control study included 73 PBC patients: 38 with SAC (PBC+SAC group, 38 eyes) and 35 controls (35 eyes). All the participants underwent comprehensive ocular surface assessment and ocular surface disease index (OSDI) scoring. The severity of ocular allergy in PBC+SAC group was indicated by total ocular symptom score (TOSS), and correlation analysis was carried out between TOSS and ocular parameters.
resultsAge (59.60±10.69y
conclusionPBC patients with SAC have higher dry eye prevalence and more severe dry eye symptoms, mainly evaporative dry eye with obvious upper meibomian gland morphological abnormalities. Allergic symptom severity is positively correlated with dry eye discomfort, suggesting allergic inflammation may exacerbate ocular surface burden in PBC patients.
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