Evidence map›Paper›PMID 41924358›Full record

ReviewFrontiers in radiology2026

Quantitative myocardial perfusion imaging across PET, SPECT, CMR, and CT.

Yoko Kato, Omar Chehab, Bharath Ambale-Venkatesh, Joao A C Lima

Abstract readReview
In one paragraph

Review in Frontiers in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yoko KatoDivision of Cardiology, Johns Hopkins University, Baltimore, MD, United States.
Omar ChehabDivision of Cardiology, Johns Hopkins University, Baltimore, MD, United States.
Bharath Ambale-VenkateshDepartment of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Joao A C LimaDivision of Cardiology, Johns Hopkins University, Baltimore, MD, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent clinical trials demonstrating the prognostic value of coronary computed tomography angiography (CCTA), and the limited incremental prognostic benefit of ischemia-guided revascularization over optimal medical therapy, have shifted focus away from functional testing. Nevertheless, myocardial perfusion assessment remains essential in patients with known or suspected coronary artery disease (CAD), microvascular dysfunction, ischemia with normal coronary arteries (INOCA), coronary anomalies, and cardiomyopathies. Advances in positron emission tomography (PET), cardiovascular magnetic resonance (CMR), and computed tomography (CT) now enable absolute quantification of myocardial blood flow (MBF), providing improved diagnostic and prognostic performance and underscoring the need to reappraise myocardial perfusion imaging. This mini-review summarizes key physiological principles, contemporary acquisition and post-processing strategies, and the clinical relevance of myocardial perfusion imaging (MPI) across PET, Single Photon Emission Computed Tomography (SPECT), CMR, and CT, and discusses future perspectives in quantitative MPI.

Indexed as

absolute myocardial blood flowcardiac magnetic resonance (CMR)computed tomography (CT)myocardial perfusion imaging (MPI)pixel-wise quantificationpositron emission tomography (PET)quantitativesingle-photon emission computed tomography (SPECT)

Identifiers

PMID41924358
PMCPMC13036148

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.