Evidence map›Paper›PMID 41924284›Full record

ReviewFrontiers in immunology2026

The microbiome: regulating anti-tumor immunity.

Yan-Lin Tao, Xin-Xin Wu, Jing-Ran Wang, Miao Liu, Ya-Nan Liu, Yong-Qi Lian, Zhao-Yu Liang, Shu-Fen Zhu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yan-Lin TaoDepartment of Intensive Care Unit, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Xin-Xin WuDepartment of Intensive Care Unit, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China.
Jing-Ran WangDepartment of Intensive Care Unit, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Miao LiuDepartment of Respiratory Medicine, Dingzhou People's Hospital, Dingzhou, China.
Ya-Nan LiuDepartment of Intensive Care Unit, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Yong-Qi LianDepartment of Intensive Care Unit, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Zhao-Yu LiangDepartment of Intensive Care Unit, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Shu-Fen ZhuPhysical Examination Center, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microorganisms distributed throughout the human body have always been a complex ecosystem that has long coexisted with other organisms. They are involved in essential key links, such as nutrient absorption, energy regulation, metabolism, toxin clearance, and immune regulation. With a deeper understanding of the microbiome, many studies have shown that the microbiome is also actively involved in the occurrence and development of tumors. The core mechanism of dysregulated microorganisms and their derivatives in the treatment response and toxicity management of tumors is the regulation of the immune function. This article explores the evolution of the microbiome and its impact on the immune function during tumor progression, and focuses on analyzing cutting-edge treatment strategies targeting the microbiome, as well as future research directions and challenges in clinical translation.

Indexed as

MicrobiotaNeoplasmsAnimalsHumansTumor Microenvironmentimmune regulatory cellsmicrobiometumortumor immunitytumor microenvironment

Identifiers

PMID41924284
PMCPMC13035494

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.