Evidence map›Paper›PMID 41924194›Full record

Articlenpj health systems2026

The evolving landscape of large language models and non-large language models in health care.

Rui Yang, Huitao Li, Matthew Yu Heng Wong, Yuhe Ke, Xin Li, Kunyu Yu, Jingchi Liao, Jonathan Chong Kai Liew, Sabarinath Vinod Nair, Jasmine Chiat Ling Ong and 6 more

Abstract read
In one paragraph

Article in npj health systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rui YangCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.
Huitao LiCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.
Matthew Yu Heng WongSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.
Yuhe KeDivision of Anesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, Singapore.
Xin LiCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.
Kunyu YuCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.
Jingchi LiaoCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.
Jonathan Chong Kai LiewCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.
Sabarinath Vinod NairCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.
Jasmine Chiat Ling OngDuke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.
Irene LiGraduate School of Engineering, The University of Tokyo, Tokyo, Japan.
Douglas TeodoroDepartment of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Chuan HongDepartment of Biostatistics and Bioinformatics, Duke School of Medicine, Durham, NC, USA.
Yifan PengDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Daniel Shu Wei TingSingapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Nan LiuCenter for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.

Funding

ClinEX - Clinical Evidence Extraction, Representation, and AppraisalR01LM014344 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Yong Chen, Yifan Peng · 2023 to 2026
$2.7M
Closing the loop with an automatic referral population and summarization systemR01LM014306 · NLM · WEILL MEDICAL COLL OF CORNELL UNIV · PI Yifan Peng, Justin Frederick Rousseau · 2023 to 2026
$2.7M
Extraction and summarization of evidence-based medicineR01LM014573 · NLM · WEILL MEDICAL COLL OF CORNELL UNIV · PI Yifan Peng, CHUNHUA WENG · 2024 to 2026
$1.1M
NLM NIH HHS R01 LM014306NLM NIH HHS R01 LM014344NLM NIH HHS R01 LM014573
6 · The paper itself

Abstract

We analyzed 19,123 natural language processing-related studies to explore the differences in task distributions and application contexts between large language models (LLMs) and non-LLM methods in health care. Through topic modeling analysis, we found that LLMs demonstrate advantages in open-ended tasks, while non-LLM methods dominate in information extraction tasks. These findings highlight the complementary strengths of the two technical paradigms and provide reference for their integration strategies in future health care applications.

Identifiers

PMID41924194
PMCPMC13038296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.