ArticleSkin health and disease2026
Highlighting a histopathological dilemma: atypical dermatofibrosarcoma protuberans diagnosed with multimodal dermoscopy.
Article in Skin health and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
An adult male agricultural worker presented with an asymptomatic, heterogeneously pigmented, indurated nodule featuring multiple protuberances on the left pelvic skin. Cross-polarized dermoscopy revealed pink structureless areas and a hyperpigmented reticular network; yellow light dermoscopy accentuated the pigmentary network and entangling vasculature. Ultraviolet-induced fluorescence dermoscopy demonstrated blue-white autofluorescence of surface keratin and milky-white fluorescence of the collagenous/myxoid stroma. Histopathology showed a monomorphic spindle-cell infiltrate without atypia; immunohistochemistry (IHC) confirmed a CD34-positive, S100-negative spindle-cell neoplasm consistent with a myxoid variant of dermatofibrosarcoma protuberans. This case highlights the diagnostic utility of multimodal dermoscopy integrated with histopathology and supportive IHC in precisely evaluating atypical cutaneous tumours.
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