Evidence map›Paper›PMID 41923803›Full record

ArticleInternational journal of developmental disabilities2026

Efficacy of vitamin/mineral supplement on children with Down syndrome and autism spectrum disorder.

Nagwa Meguid, Hala Zeidan, Adel Hashish, Sherien Nasser, Fatma Hussein, Maha Hemimi, Neveen Nashaat

Abstract read
In one paragraph

Article in International journal of developmental disabilities, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nagwa MeguidResearch on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre.ORCID https://orcid.org/0000-0002-7962-2501
Hala ZeidanResearch on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre.ORCID https://orcid.org/0000-0001-7631-9286
Adel HashishResearch on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre.ORCID https://orcid.org/0000-0001-9549-2973
Sherien NasserResearch on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre.ORCID https://orcid.org/0000-0003-2897-7676
Fatma HusseinResearch on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre.ORCID https://orcid.org/0000-0001-6097-8121
Maha HemimiResearch on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre.ORCID https://orcid.org/0000-0003-2185-0840
Neveen NashaatResearch on Children with Special Needs Department, Medical Research and Clinical Studies Institute, National Research Centre.ORCID https://orcid.org/0000-0003-1553-9327

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The management of language deficits and therapeutic efficacy of micronutrients supplementation in improving presentations in Down syndrome (DS) and autistic children are very challenging. The aim of this open-label study is to explore the effect of micronutrients supplementation together with language stimulating environment on language abilities, the severity of autism spectrum spectrum (ASD) presentations, and on serum levels of some micronutrients and serotonin in these children. Methods: DS and autistic children ( Results: All the participants showed improved language abilities ( Conclusions: This research provides further support for the benefits of dietary supplementation with home-based language stimulation for DS and autistic children.

Indexed as

autismDown syndromefamily-based interventionlanguagemicronutrients supplementation

Identifiers

PMID41923803
PMCPMC13037151

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.