Evidence map›Paper›PMID 41923763›Full record

ArticleFrontiers in public health2026

Periodontal therapy among patients with cardiovascular disease: exploring its association with lower medical spending.

Morgan Santoro, Caroline McLeod, Lisa J Heaton, Hannah J Cheung, John J O'Malley, Madison Vinson, Rebecca A Preston, Eric P Tranby

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Morgan SantoroCareQuest Institute for Oral Health, Boston, MA, United States.
Caroline McLeodCareQuest Institute for Oral Health, Boston, MA, United States.
Lisa J HeatonCareQuest Institute for Oral Health, Boston, MA, United States.
Hannah J CheungCareQuest Institute for Oral Health, Boston, MA, United States.
John J O'MalleyCareQuest Institute for Oral Health, Boston, MA, United States.
Madison VinsonCareQuest Institute for Oral Health, Boston, MA, United States.
Rebecca A PrestonCareQuest Institute for Oral Health, Boston, MA, United States.
Eric P TranbyCareQuest Institute for Oral Health, Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cardiovascular disease (CVD) and periodontal disease are prevalent chronic conditions that share common risk factors and may be linked through systemic inflammation. Emerging evidence suggests that individuals with periodontal disease are more likely to be diagnosed with CVD, potentially influencing health care costs. Methods: This study analyzed deidentified commercial insurance claims data from 192,500 United States (U. S.) adults aged 21-64 with CVD diagnoses between 2015 and 2022. Patients were categorized based on periodontal treatment received in 2020-2021: none, 1-3 visits, or 4 + visits. Gamma regression and multinomial propensity score matching (PSM) models assessed associations between periodontal treatment and 2022 health care costs (overall, outpatient, inpatient, and prescription), controlling for demographic and clinical covariates. Reported percentage reductions and average treatment effect on treated (ATET) dollar difference reflect estimates derived from PSM-weighted models. Results: Patients with four or more periodontal visits had significantly lower overall medical costs (9.6% reduction; ATET = -$1,960.39, 95% confidence interval (CI) = -$2,684.33, -$1,236.44, Conclusion: Findings suggest that periodontal treatment may be associated with lower health care costs among individuals with CVD, potentially attributed to reduced systemic inflammation. The cost differences were most pronounced with four or more periodontal visits, supporting risk-based recall strategies. These results underscore the relevance of integrating oral health into chronic disease management and indicate that greater access to periodontal care may be associated with economic and health benefits.

Indexed as

Cardiovascular DiseasesHealth Care CostsHealth ExpendituresPeriodontal DiseasesAdultFemaleHumansMaleMiddle AgedUnited StatesYoung Adultcardiovascular diseasecommercial insurancegamma regression analysisperiodontal diseasepropensity score matching

Identifiers

PMID41923763
PMCPMC13036156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.