Evidence map›Paper›PMID 41923722›Full record

ArticleReviews in cardiovascular medicine2026

Three-Dimensional Echocardiographic Evaluation of Rheumatic Tricuspid Valve Disease: A Prospective Single-Center Cohort Study.

Mahmoud Abdelnabi, Abdallah Almaghraby, Moustafa Gamal, Mohamed Ayman Abdel-Hay, Hoda Abdelgawad

Abstract read
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Article in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mahmoud AbdelnabiDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID https://orcid.org/0000-0001-8016-9049
Abdallah AlmaghrabyDepartment of Cardiology, Ibrahim Bin Hamad Obaidallah Hospital, 10190 Ras Al Khaimah, UAE.
Moustafa GamalDepartment of Cardiology, Faculty of Medicine, Alexandria University, 5372066 Alexandria, Egypt.
Mohamed Ayman Abdel-HayDepartment of Cardiology, Faculty of Medicine, Alexandria University, 5372066 Alexandria, Egypt.
Hoda AbdelgawadDepartment of Cardiology, Faculty of Medicine, Alexandria University, 5372066 Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rheumatic heart disease (RHD) remains a prevalent cause of valvular heart pathology worldwide, especially in younger populations of low- and middle-income countries. Tricuspid valve (TV) involvement in RHD is usually secondary to left-sided valvular lesions and is often underdiagnosed, since two-dimensional echocardiography (2DE) has limited ability to visualize the complex tricuspid anatomy. Compared with 2DE, three-dimensional echocardiography (3DE) provides an en face visualization of the tricuspid valve, enabling direct planimetric measurements and detailed commissural assessment, and offers advantages for evaluating complex valvular heart disease (VHD). Thus, this study aimed to assess baseline characteristics and valvular morphology in patients with rheumatic tricuspid valve disease using 3DE. Methods: A prospective cohort single-center study conducted between April 2022 and April 2023 included 34 patients with rheumatic TV involvement. Baseline demographics, morphological features, and hemodynamic parameters were assessed using transthoracic 3DE. Results: The mean age of included patients was 45.5 ± 9.1 years, and 88.2% were female. Most patients had associated left-sided valvular involvement (mitral or combined mitral and aortic). Commissural fusion (50%), leaflet thickening (82.4%), restricted mobility (85.3%), and coaptation loss (58.8%) were predominantly noted. The mean diastolic TV gradient was 3.9 ± 3.4 mmHg, planimetry area 3.3 ± 1.7 cm Conclusion: Rheumatic TV involvement is characterized by commissural fusion, leaflet thickening, and coaptation loss, highlighting the diagnostic value of 3DE in identifying morphological patterns that may guide intervention planning.

Indexed as

2D echocardiography3D echocardiographycommissural fusionrheumatic heart diseasethicknesstricuspid valvevalvular morphology

Identifiers

PMID41923722
PMCPMC13036517

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