ArticleActa anaesthesiologica Scandinavica2026
Effects of Peri-Operative Glucocorticoids in Hip Fracture Patients on Post-Operative Outcomes: Systematic Review Protocol.
Article in Acta anaesthesiologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effects of Peri-Operative Glucocorticoids in Hip Fracture Patients on Post-Operative Outcomes: Systematic Review Protocol.Acta anaesthesiologica Scandinavica · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHip fracture patients are often elderly and frail, with a high burden of comorbidity, placing them at substantial risk of post-operative delirium and other complications. Post-operative delirium is associated with prolonged recovery, functional decline, increased mortality and higher healthcare costs. Peri-operative glucocorticoids are widely used in peri-operative care and may modulate the inflammatory response associated with surgery, potentially reducing delirium and related adverse outcomes. AIM AND HYPOTHESIS: This systematic review aims to evaluate the effects of peri-operative glucocorticoids on post-operative delirium in adults undergoing hip fracture surgery, as well as associated benefits and harms.
methodThis protocol follows Cochrane methodology and PRISMA recommendations. The research question will be structured using the PICO framework. Randomised controlled trials and observational studies comparing peri-operative glucocorticoids with placebo or no peri-operative glucocorticoids will be included. The primary outcome is post-operative delirium incidence. Secondary outcomes include delirium severity, post-operative pain, morphine equivalents, patient satisfaction, length of stay, other adverse events as defined by author, and mortality. A comprehensive literature search will be conducted in multiple databases, supplemented by reference screening and searches for ongoing or unpublished studies. Meta-analysis will be performed where appropriate. Heterogeneity will be assessed, and subgroup or sensitivity analyses conducted as needed. Risk of bias and quality of evidence will be assessed using validated tools, and certainty of evidence will be evaluated using GRADE. DISCUSSION: This review will synthesise current evidence on the efficacy and safety of peri-operative glucocorticoids in hip fracture surgery, with a particular focus on post-operative delirium. The findings may inform clinical practise and guide future research in this vulnerable patient population.
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