Evidence map›Paper›PMID 41923473›Full record

ArticleAging & mental health2026

Childhood mental health and major depression in later life: a survival analysis across 12 years.

Xiaoling Xiang, Xiafei Wang, Xinyin Zhang, Josephine Abrials

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging & mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoling XiangSchool of Social Work, University of Michigan, Ann Arbor, MI, USA.
Xiafei WangCollege of Social Work, University of Kentucky, Lexington, KY, USA.
Xinyin ZhangCollege of Literature, Science, and the Arts, University of Michigan, Ann Arbor, MI, USA.
Josephine AbrialsCollege of Literature, Science, and the Arts, University of Michigan, Ann Arbor, MI, USA.

Funding

Community-Embedded, Layperson-Supported Digital Mental Health Intervention for Homebound Older Adults with Depression: A Type 1 Hybrid Effectiveness-Implementation RCTR01MH137064 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Xiaoling Xiang · 2024 to 2026
$2.1M
ACL HHS 90IFRE0097NIMH NIH HHS R01 MH137064
6 · The paper itself

Abstract

objectivesThis study examined the relationship between childhood mental health conditions and incident major depression in middle-aged and older adults.

methodThis longitudinal panel study used 12 years of data from 27,220 adults aged 51 and older in the U.S. Health and Retirement Study. Childhood mental health conditions were assessed retrospectively with a question about having a depression, drug/alcohol, or other emotional problem before age 16. Cox regression was used to estimate hazard ratios (HRs).

resultsChildhood mental health conditions were reported by 6.04% of the unweighted sample (

conclusionChildhood mental health condition has long-lasting consequences for depression risk in later life.

Indexed as

Adverse Childhood ExperiencesMajor Depressive DisorderAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedRetrospective StudiesSurvival AnalysisUnited Stateschildhood mental healthgeriatric depressionHealth and Retirement StudyLife coursemajor depression

Identifiers

PMID41923473
PMCPMC13053148

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.