Evidence map›Paper›PMID 41923243›Full record

Observational studyJournal of translational medicine2026

Optimal nap timing and body mass index: beyond duration.

Giovana Longo-Silva, María Rodríguez-Martín, Diego Salmerón, Frank A J L Scheer, Marta Garaulet

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Journal of translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03036592 (MTNR1B SNP*Food Timing Interaction on Glucose Control in a Late Eater Mediterranean Population), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03036592 nacompletednot on this map

MTNR1B SNP*Food Timing Interaction on Glucose Control in a Late Eater Mediterranean Population

TypeinterventionalSponsorUniversidad de MurciaRan2017 to 2020Enrolled889ConditionsNon-Diabetic Disorder of Endocrine PancreasArmsEarly OGTT, Late OGTT
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giovana Longo-SilvaDepartment of Physiology, University of Murcia, Murcia, Spain. giovana.silva@fanut.ufal.br.ORCID 0000-0003-0776-0638
María Rodríguez-MartínDepartment of Physiology, University of Murcia, Murcia, Spain.ORCID 0000-0002-9877-7728
Diego SalmerónEpidemiology and Public Health, Biomedical Research Institute of Murcia Pascual Parrilla-IMIB, Murcia, Spain.ORCID 0000-0002-4574-6880
Frank A J L ScheerDivision of Sleep Medicine, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2014-7582
Marta GarauletDepartment of Physiology, University of Murcia, Murcia, Spain. garaulet@um.es.ORCID 0000-0002-4066-3509

Funding

Impact of Malatonin, Food Timing and Receptor Variant on Type 2 Diabetes RiskR01DK105072 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI SAXENA, RICHA, SCHEER, FRANK A · 2016 to 2020
$3.2M
NIDDK NIH HHS R01 DK105072
6 · The paper itself

Abstract

backgroundOverweight and obesity continue to rise globally, and sleep has emerged as an important behavioral determinant of body weight. While nighttime sleep has been widely studied, the role of daytime napping-especially nap timing-remains unclear. Existing research relies on clock time, which may not reflect individual rhythms. This study investigates whether nap timing referenced to daily events is associated with BMI in two adult populations of habitual nappers (Spain and Brazil). Secondary aims included the association of nap duration and weekend-weekday differences in nap timing and duration with BMI.

methodsHabitual nappers (n = 3550) aged 18-65 years were studied. Nap timing was calculated relative to wake time and lunch time. As secondary analyses, nap duration and weekend-weekday differences in nap timing (nap jet lag) and in nap duration were evaluated. Linear regression and restricted cubic spline models were applied.

resultsBMI and excess weight prevalence were similar between countries. Compared with Spaniards, Brazilians showed earlier naps (by >2 h), longer weekend naps (by 13 min), and greater nap jet lag (by 23 min) (all p < 0.001). Despite these differences, no significant interactions by country were observed in nap-BMI associations, and data were pooled. Nap timing relative to wake and lunch displayed L-shaped associations with BMI: the highest BMI corresponded to early naps (~3h after waking and ~2h before lunch), whereas the lowest BMI (i.e. the inflection points) occurred when naps were 7h18min after wake (β = -0.48 kg/m

conclusionsFindings highlight nap timing as a novel behavioral factor associated with BMI, warranting further longitudinal research to explore its potential causal role.

trial registrationClinicalTrials.gov NCT03036592 (ONTIME-MT).

Indexed as

Body Mass IndexSleepAdolescentAdultAgedBrazilCircadian RhythmFemaleHumansMaleMiddle AgedSleep DurationSpainTime FactorsYoung AdultCircadian misalignmentDaytime sleepNap timingObesitySiestaSocial jet lag

Identifiers

PMID41923243
PMCPMC13188648

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.