Evidence map›Paper›PMID 41923200›Full record

ArticleBMC infectious diseases2026

Evaluation of diagnostic practices and treatment compliance for Chlamydia trachomatis and Neisseria gonorrhoeae in male patients at STD clinics in Southern China.

Mingzhou Xiong, Zichao Pang, Xiangyi He, Mengqi Gao, Peizhen Zhao, Shujie Huang, Jinqi Li, Menglan Yang, Cheng Wang

Abstract read
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Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mingzhou XiongDermatology Hospital of Southern Medical University, Guangzhou, China. lewnxiong@163.com.
Zichao PangSchool of Public Health, Southern Medical University, Guangzhou, China.
Xiangyi HeGuangdong Provincial Key Laboratory of Tropical Diseases Research, School of Public Health, Southern Medical University, Guangzhou, China.
Mengqi GaoDermatology Hospital of Southern Medical University, Guangzhou, China.
Peizhen ZhaoDermatology Hospital of Southern Medical University, Guangzhou, China.
Shujie HuangDermatology Hospital of Southern Medical University, Guangzhou, China.
Jinqi LiCenter for Disease Control and Prevention of Baiyun District, Guangzhou, China.
Menglan YangSchool of Public Health, Guizhou Medical University, Guiyang, China.
Cheng WangDermatology Hospital of Southern Medical University, Guangzhou, China. wangcheng090705@gmail.com.

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2022A1515110895Guangdong University Youth Innovation Talent Project 2021KQNCX011
6 · The paper itself

Abstract

objectivesTo evaluate the diagnostic accuracy and adherence to national treatment guidelines for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) among male patients attending sexually transmitted disease (STD) clinics (MSPs) in southern China.

methodsA survey was conducted in Guangdong Province in 2022. MSPs who completed standard clinical procedures provided informed consent and an additional urine sample for CT/NG testing at the reference laboratory. Information of reference laboratory-confirmed CT/NG cases were extracted from hospital information systems. Clinic-reported test results were compared to reference laboratory findings. Treatment records were reviewed to assess compliance with national STD treatment guidelines.

resultsAmong 5,354 participants, the reference laboratory confirmed 96 CT-positive and 71 NG-positive cases. In clinical settings, 22 (22.9%) CT-positive and 7 (9.9%) NG-positive patients were not tested for the relevant pathogen. Of those tested, clinics identified only 24 (32.4%) CT-positive and 38 (59.4%) NG-positive cases. True-positive proportions for CT were 60.0% (NAAT), 31.3% (antigen detection), and 0% (culture). For NG, the corresponding proportions were 100.0% (NAAT), 59.5% (Gram stain smear), and 57.7% (culture). Among CT-positive patients, 27 received treatment, but only 5 (22.7%) received guideline-recommended regimens. Of 38 NG-positive patients who received treatment, only 16 (42.1%) were treated appropriately.

conclusionsDiagnostic performance and adherence to recommended treatment regimens for CT and NG among MSPs in southern China remain inadequate. Efforts are needed to expand testing coverage, upgrade diagnostic tools, and improve compliance with national treatment guidelines to reduce the burden of CT and NG infections in this population.

Indexed as

Chlamydia InfectionsChlamydia trachomatisGonorrheaNeisseria gonorrhoeaePatient ComplianceAdolescentAdultChinaGuideline AdherenceHumansMaleMiddle AgedYoung AdultChlamydia trachomatisCross-sectional studyLaboratory testNeisseria gonorrhoeaeTreatment

Identifiers

PMID41923200
PMCPMC13169930

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.