Evidence map›Paper›PMID 41923116›Full record

ReviewMaternal health, neonatology and perinatology2026

Early dyadic interventions for critically ill neonates: a scoping review.

Mariana C Aokalani, Louisa Flynn, Anniette Maldonado, Katherine L Wisner, Catherine Limperopoulos, Nickie N Andescavage

Abstract readReview
In one paragraph

Review in Maternal health, neonatology and perinatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mariana C AokalaniChildren's National Hospital, Washington, District of Columbia, USA.ORCID https://orcid.org/0009-0005-2774-4813
Louisa FlynnChildren's National Hospital, Washington, District of Columbia, USA.
Anniette MaldonadoChildren's National Hospital, Washington, District of Columbia, USA.
Katherine L WisnerChildren's National Hospital, Washington, District of Columbia, USA.ORCID https://orcid.org/0000-0003-3458-5986
Catherine LimperopoulosChildren's National Hospital, Washington, District of Columbia, USA. CLimpero@childrensnational.org.ORCID https://orcid.org/0000-0002-6191-416X
Nickie N AndescavageChildren's National Hospital, Washington, District of Columbia, USA.ORCID https://orcid.org/0000-0003-1735-0069

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly dyadic interventions improve parental mental health, infant development, and parent-infant relationships. We reviewed and synthesized existing research on early dyadic interventions with a neonatal intensive care unit (NICU) inpatient component, with an emphasis on psychotherapeutic approaches. We mapped the available evidence and identified gaps in the literature. Followed PRISMA-ScR reporting guidelines.

methodsSearch engines used:PubMed, MEDLINE, MEDLINE Plus, EBSCO, Cochrane Central, Google Scholar, and Science.gov. Key search terms included “dyadic interventions in the NICU,” NICU dyadic health,” “attachment-focused interventions in NICU, ‘neonatal intensive care unit, “Early Relational interventions” and “relational interventions in the NICU.” English papers between 2014 and 2024. Feasibility, physical and/or mental health, and relational outcome measures were included. Nine of the 2331 papers reviewed met the inclusion criteria. Extracted author, year of publication, intervention type, study design, sample characteristics, location outcomes, mental health intervention, and the number of early dyadic interventions included.

resultsAll early dyadic interventions improved parents’ mental health, infant neurodevelopment, and parent-infant relationships. We found substantial heterogeneity across included studies in terms of study design, sample characteristics, operationalization of dyadic intervention, and outcome measures. However, most interventions were not psychotherapy; more detailed research is needed to understand the long-term impact of early psychotherapeutic dyadic interventions.

conclusionInfant and Early Childhood dyadic interventions have yet to be studied in the inpatient NICU setting. This highlights a critical need for research to study the feasibility and impact of infant mental health dyadic interventions for this vulnerable population in this setting.

Indexed as

AttachmentBondingDyadic interventionsInfant mental healthNICU parent-infant relationship

Identifiers

PMID41923116
PMCPMC13045093

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.