Evidence map›Paper›PMID 41922884›Full record

ArticleMolecular imaging and biology2026

Preclinical Study of Radiolabeled LyP-1 for Detecting Sunitinib-induced Changes in the Tumor Microenvironment and Synergistic Antitumor Effects in Triple-negative Breast Cancer.

Sisi Liao, Qinli Qi, Lifang Jin, Jiali Gong, Lingzhou Zhao, Jinhua Zhao, Meilin Zhu, Ningning Song

Abstract read
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Article in Molecular imaging and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sisi Liao *Department of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People's Republic of China.
Qinli Qi *Department of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People's Republic of China.
Lifang Jin *Department of Ultrasound, Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, 201619, People's Republic of China.
Jiali GongDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People's Republic of China.
Lingzhou ZhaoDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People's Republic of China.
Jinhua ZhaoDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People's Republic of China. zhaojinhua1963@126.com.
Meilin ZhuSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, 750004, Ningxia, People's Republic of China. jay70281@163.com.
Ningning SongDepartment of Breast Surgery, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, People's Republic of China. sonini00@163.com.

Funding

National Natural Science Foundation of China 82202212
6 · The paper itself

Abstract

purposeSunitinib is an anti-angiogenic drug that can induce drug resistance characterized by hypoxia. We aimed to synthesize two novel radiolabeled LyP-1 peptides,

methodsWe synthesized

results

Indexed as

Antineoplastic AgentsIndolesPeptides, CyclicPyrrolesSunitinibTriple Negative Breast NeoplasmsTumor MicroenvironmentAnimalsCell Line, TumorDrug SynergismFemaleHumansMiceMice, Inbred BALB CTissue DistributionXenograft Model Antitumor AssaysAntineoplastic AgentsIndolesLyP-1 peptidePeptides, CyclicPyrrolesSunitinibLyP-1Micro-SPECT/CTSunitinibTriple-negative breast cancer

Identifiers

PMID41922884

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.