ArticleInternational journal of obesity (2005)2026
Beyond mean and maximum CO₂: introducing hypercapnic burden as a marker of sleep-related hypoventilation.
Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesIn obesity hypoventilation syndrome (OHS), nocturnal hypoventilation can precede daytime respiratory failure. Therefore, the hypercapnic burden index was introduced to quantify sleep-related CO₂ retention.
methodsThirty-one patients who underwent polysomnography with transcutaneous capnography and met OHS criteria were retrospectively included in this single-center cross-sectional study. The area above the predetermined transcutaneous partial pressure of CO
resultsVery strong positive correlations were revealed between maxCO
conclusionThis underscores the heterogeneity of nocturnal hypoventilation in OHS and the potential value of more nuanced markers in individual patients, as daytime hypercapnia might not be present yet, and maxCO
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