Evidence map›Paper›PMID 41922488›Full record

ArticleSpinal cord2026

Relationship of prescription and nonprescription opioid use, opioid misuse, and alcohol use with suicidal ideation among people with spinal cord injury.

James S Krause, Clara E Dismuke-Greer, Devyn E Smith, Nicole D Dipiro

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Article in Spinal cord, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James S KrauseCollege of Health Professions, Medical University of South Carolina, Charleston, SC, USA. krause@musc.edu.ORCID http://orcid.org/0000-0001-8129-5389
Clara E Dismuke-GreerHealth Economics Resource Center, Veterans Affairs Palo Alto Health Care System, Menlo Park, CA, USA.
Devyn E SmithCollege of Health Professions, Medical University of South Carolina, Charleston, SC, USA.
Nicole D DipiroCollege of Health Professions, Medical University of South Carolina, Charleston, SC, USA.ORCID http://orcid.org/0000-0003-1459-4690

Funding

ACL HHS 90DPHF0009
6 · The paper itself

Abstract

STUDY

designCross-sectional study.

objectiveTo identify the relationship of prescription opioid use, self-reported misuse of opioids, and binge drinking days with suicidal ideation (SI) in a cohort of participants with spinal cord injury (SCI).

settingMedical university in the southeastern United States.

methodsThis was a cross-sectional analysis of self-report data from 1253 study participants with SCI, all of whom were enrolled in a longitudinal study of health outcomes. SI was assessed and dichotomized using item 9 on the Patient Health Questionnaire-9.

resultsOccasional use of 3 or more prescription opioids was associated with greater odds of SI (OR = 3.53, CI = 1.50-8.31), as was self-reported misuse of prescription opioids (OR = 3.51, CI = 1.83-6.72). Days of binge drinking was unrelated to SI. Odds of SI were higher for those with depression (OR = 5.98, CI = 3.60-9.92) and those who reported 15 or more painful days in a month (OR = 2.15, CI = 1.24-3.73). Compared with the most severe SCI (high cervical, non-ambulatory), participants who were ambulatory (OR = 0.36, CI = 0.15-0.86) or were non-cervical/non-ambulatory (OR = 0.32, CI = 0.14-0.75) reported lower odds of SI.

conclusionsPrescription opioid use needs to be closely monitored by healthcare professionals for those who use multiple opioids and who self-report misusing opioids, as there is a relationship with SI, even when considering multiple covariates pain and depression.

Indexed as

Alcohol DrinkingAnalgesics, OpioidOpioid-Related DisordersPrescription Drug MisuseSpinal Cord InjuriesSuicidal IdeationAdultCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedSelf ReportAnalgesics, Opioid

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.