Evidence map›Paper›PMID 41922459›Full record

ArticleScientific reports2026

Multidisciplinary expert evaluation of large language models on questions regarding bariatric surgery: a comparative analysis of ERNIE Bot 4.0, ChatGPT-4, Claude 3 Opus, and Gemini Pro.

Jianshu Cai, Jionghuang Chen, Tingting Yu, Lifang He, Liuliu Chen, Haiou Qi, Xinju Zhan, Weihua Yu, Xiaoling Huang, Pengyu Huang

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jianshu Cai *Nursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jionghuang Chen *Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China.
Tingting YuNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Lifang HeSchool of Nursing, Xiangnan University, Chenzhou, China.
Liuliu ChenDepartment of Nursing, The Fifth Affiliated Hospital of Zunyi Medical University, Zhuhai, Guangdong Province, China.
Haiou QiNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xinju ZhanNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Weihua YuSchool of Nursing, The University of Hong Kong, Hong Kong, China.
Xiaoling HuangNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Pengyu HuangFujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics &Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China. huangpengyu@bjmu.edu.cn.

Funding

Hunan Province Undergraduate Innovation and Entrepreneurship Training Program S202510545100Joint Funds for the innovation of science and Technology Fujian province 2023Y9384Medical Science and Technology Project of Zhejiang Province 2023KY781NO.2025QNGGA010 backbone project of Fujian provinceScience and Technology and Health Commission of Guizhou Province GZWKJ2021-491Zhejiang Provincial Natural Science Foundation of China LQ24H160021
6 · The paper itself

Abstract

Large language models (LLMs) have potential in bariatric surgery consultations, but current evaluations are limited to bariatric specialists, contradicting guidelines that call for multidisciplinary assessment. This study uses a multidisciplinary framework to evaluate LLM performance on bariatric surgery queries. Four LLMs (ERNIE Bot 4.0, ChatGPT-4, Claude 3 Opus, and Gemini Pro) were tested on 50 common bariatric surgery questions, generating 200 responses. A panel of seven experts (4 bariatric surgeons, 1 obesity physician, and 2 dietitians) assessed accuracy and comprehensiveness. Three prompt approaches were used to evaluate self-correction: basic review, web-enabled review, and evidence-based review. Qualitative analysis identified poorly rated responses. The study adheres to TRIPOD-LLM Statement reporting guideline. Rater agreement was fair, accuracy rating, Fleiss’ kappa = 0.210 (95% CI: 0.208–0.212; Z = 7.815; P < 0.001); comprehensiveness rating, Fleiss’ kappa = 0.464 (95% CI: 0.453–0.476; Z = 2.543; P < 0.011). Claude 3 Opus provided the longest answers, while ERNIE Bot 4.0 had the highest accuracy (19.46 ± 2.07). ChatGPT-4 had 90.0% “good” responses, compared to 84.0% for ERNIE Bot 4.0, 80.0% for Claude 3 Opus, and 48.0% for Gemini Pro (P ≤ 0.05). All LLMs performed sub-optimally in comprehensiveness (scores: 2.86–3.13 out of 5). However, they showed significant self-correction capabilities, especially when using internet searches and evidence-based resources. LLMs show potential for bariatric surgery education, but their direct clinical use is challenging due to variable accuracy and suboptimal comprehensiveness. Future efforts should focus on developing specialized LLMs with robust evidence and multidisciplinary input to ensure patient safety and optimal outcomes.

Indexed as

Bariatric SurgeryLarge Language ModelsHumansbariatric surgerychatbotChatGPTClaudeERNIE BotGemini Prolarge language modelsmultidisciplinary expert

Identifiers

PMID41922459
PMCPMC13199474

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.