Evidence map›Paper›PMID 41922194›Full record

ArticleEmerging infectious diseases2026

Tropism and Replication Competence of Cattle Influenza A(H5N1) Genotype B3.13 Virus in Human Bronchus and Lung Tissue.

Kenrie P Y Hui, John C W Ho, Ka-Chun Ng, Richard J Webby, Malik Peiris, John M Nicholls, Michael C W Chan

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kenrie P Y Hui
John C W Ho
Ka-Chun Ng
Richard J Webby
Malik Peiris
John M Nicholls
Michael C W Chan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2024, influenza A(H5N1) genotype B3.13 viruses emerged from cattle and caused mild spillover infections in humans. Using human bronchus and lung tissue, we evaluated tropism, replication, and pathogenesis of 2 cattle influenza isolates. Those viruses showed moderate replication competence and induced robust proinflammatory responses, suggesting potential risk for human health.

Indexed as

BronchiCattle DiseasesInfluenza A Virus, H5N1 SubtypeInfluenza, HumanLungOrthomyxoviridae InfectionsViral TropismVirus ReplicationAnimalsCattleGenotypeHumanscattle influenzacytokineex vivoH5N1Hong Konghuman respiratory tractinflammatoryInfluenzarespiratory infectionsviruseszoonoses

Identifiers

PMID41922194
PMCPMC13175097

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.