Evidence map›Paper›PMID 41922084›Full record

ArticleJournal for immunotherapy of cancer2026

PD-L1-targeted PET imaging for non-invasive assessment of immunotherapy response in lung cancer.

Yang Chen, Xiufeng Liu, Yinting Hu, Ao Li, Baozhen Zeng, Peng Wang, Ganghua Tang, Benyuan Jiang, Hui Yuan, Lei Jiang

Abstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yang Chen *PET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Xiufeng Liu *PET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Yinting Hu *PET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Ao Li *Department of Pulmonary Surgery, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Baozhen ZengDepartment of Pathology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Peng WangPET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Ganghua TangNanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Benyuan JiangDepartment of Pulmonary Surgery, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China jianglei6814@gdph.org.cn yuanhui@gdph.org.cn jiangbenyuan@gdph.org.cn.
Hui YuanPET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China jianglei6814@gdph.org.cn yuanhui@gdph.org.cn jiangbenyuan@gdph.org.cn.
Lei JiangPET Center, Department of Nuclear Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China jianglei6814@gdph.org.cn yuanhui@gdph.org.cn jiangbenyuan@gdph.org.cn.ORCID http://orcid.org/0000-0002-9479-132X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune checkpoint inhibitors have improved outcomes for several malignancies; however, there remains a lack of accurate, non-invasive methods to assess tumor PD-L1 expression levels and guide immunotherapy. This study aimed to evaluate the role of PD-L1-targeted positron emission tomography (PET) imaging in predicting immunotherapy response and prognosis in lung cancer.

methodsFour healthy volunteers and 22 treatment-naïve lung cancer patients were prospectively enrolled and underwent [

resultsLesions with high PD-L1 expression exhibited significantly higher [

conclusions[

Indexed as

B7-H1 AntigenImmunotherapyLung NeoplasmsPositron-Emission TomographyAdultAgedFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPrognosisProspective StudiesTreatment OutcomeB7-H1 AntigenCD274 protein, humanFluorodeoxyglucose F18fMRI / PETImmunotherapyLung Cancer

Identifiers

PMID41922084
PMCPMC13052615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.