Clinical outcomes of tooth autotransplantation: a systematic review and meta-analysis of survival.

Objectives: Autotransplantation is a procedure that involves the extraction and transplantation of a tooth from one site to another within the same individual. This systematic review and meta-analysis aimed to investigate how clinical outcomes of autotransplanted teeth evolve over time and the principal reasons for extraction. Methods: Studies were identified from five databases. A meta-analysis was performed to estimate the survival rates in the short-term (1 to ≤4 years), medium-term (>4 to ≤8 years), and long-term (>8 years) periods. Subgroup analysis was performed for age and root development. Risks of bias, reasons for extraction, and patient-reported outcome measures were evaluated. Results: Of the 3,941 reports initially identified, 46 were included. The estimated short-, medium-, and long-term survival rates were 96.31% (95% confidence interval [CI], 94.80-97.82), 88.23% (95% CI, 85.59-90.87), and 84.80% (95% CI, 76.70- 92.91), respectively. There were no significant differences in outcomes between age and root development groups. The most common reason for tooth loss was root resorption. High patient satisfaction rates were reported. Conclusions: Autotransplanted teeth exhibit high survival rates in the short- to medium-term. Minimizing root surface damage and excluding pulpal contaminants may promote longevity. The procedure appeared equally successful for teeth at different stages of root development and across various age groups.