ArticleThe Journal of clinical endocrinology and metabolism2026
Mapping of sex hormones in the testicular vein of healthy men.
Article in The Journal of clinical endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mapping of sex hormones in the testicular vein of healthy men.The Journal of clinical endocrinology and metabolism · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
contextThe testis produces hormones controlling sex differentiation, development, and reproduction. Their quantification in physiological conditions can aid our understanding of the endocrine function of the testis.
objectiveTo measure the concentrations of steroid hormones and FSH, LH, inhibin B, anti-Müllerian hormone (AMH), and insulin-like factor 3 (INSL3) in the testicular and femoral veins, femoral artery, and seminal fluid in healthy men.
designSample collection was made by angiographic catheterization under fluoroscopy from the testicular and femoral veins. Femoral artery samples were collected via needle puncture and seminal fluid was isolated from semen samples. Hormones were measured via liquid chromatography mass spectrometry and immunoassays.
participantsSeven volunteers (aged 22-49 years) without self-reported diseases and normal semen quality were included. MAIN OUTCOMES: Concentrations of steroid hormones, FSH, LH, inhibin B, AMH, and INSL3 in the testicular vein, femoral artery, femoral vein, and seminal fluid.
resultsExpectedly, testosterone was 66-fold higher in the testicular vein compared to the femoral artery, but surprisingly, levels of 11-deoxycortisol and 11-deoxycorticosterone were 4- and 20-fold higher in the testicular vein compared to the femoral artery. In line with their production site in the testis, INSL3 and inhibin B were 200- and 2-fold higher in the testicular vein compared to the femoral artery. Unexpectedly, concentration of AMH was not different between the testicular vein and femoral artery despite its documented production in the testis. CONCLUSION AND RELEVANCE: Our results provide insight into the endocrine function of the testis under physiological conditions and constitute a reference for further research in male reproductive function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.