Evidence map›Paper›PMID 41920463›Full record

ArticleDigestive diseases and sciences2026

Investigating Handgrip Strength as a Practical Biomarker for Therapeutic Endpoints and Nutritional Status in Patients with Inflammatory Bowel Disease.

Andreas Vadarlis, Georgios Germanidis, Theofanis Maris, Manousos George Pramateftakis, Michail Chourdakis

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andreas VadarlisLaboratory of Hygiene, Social & Preventive Medicine and Medical Statistics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, University Campus, 54124, Thessaloniki, Greece. vadarlisandrew@gmail.com.ORCID http://orcid.org/0000-0001-6130-7127
Georgios GermanidisDivision of Gastroenterology, First Department of Internal Medicine, "AHEPA" University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Theofanis MarisDepartment of Gastroenterology, General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, Greece.
Manousos George PramateftakisFourth Surgical Department, School of Medicine, General Hospital of Thessaloniki "G. Papanikolaou", Aristotle University of Thessaloniki, Thessaloniki, Greece.
Michail ChourdakisLaboratory of Hygiene, Social & Preventive Medicine and Medical Statistics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, University Campus, 54124, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCurrent biomarkers for inflammatory bowel disease (IBD) often rely on invasive procedures and lack broad availability, limiting their utility in clinical practice. This study aims to investigate the association between handgrip strength (HGS) and crucial treatment endpoints in IBD, such as disease activity, endoscopic severity and nutritional status in patients with IBD.

methodsThis double-center study enrolled patients with Crohn's disease (CD) and ulcerative colitis (UC). The disease activity, endoscopic severity, health-related quality of life (HRQoL) and presence of depressive disorder were evaluated using validated scores. HGS was measured through a calibrated isokinetic dynamometer and the nutritional status of the participants was assessed. A statistical software was used to analyze the data.

resultsA total of 144 patients were included in this study. A statistically significant correlation was found between HGS and disease activity (r

conclusionHGS correlates with crucial endpoints in IBD, with an acceptable accuracy for malnutrition diagnosis. These findings support the value of HGS as an indicator of overall health and nutritional status in routine clinical practice. While normalization of HGS values could be considered a meaningful goal, further prospective studies are necessary to validate its prognostic role in IBD.

Indexed as

Colitis, UlcerativeCrohn DiseaseHand StrengthNutritional StatusAdultBiomarkersDepressionFemaleHumansMaleMiddle AgedQuality of LifeSeverity of Illness IndexBiomarkersBiomarkerHandgrip strengthInflammatory bowel disease

Identifiers

PMID41920463
PMCPMC13500410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.