Evidence map›Paper›PMID 41920403›Full record

ArticleOdontology2026

Evaluation of the effects of ultraviolet photofunctionalization on titanium surfaces: in vitro and in vivo study.

Bruno Dos Santos Pavei, André Antonio Pelegrine, Henrique Ballassini Abdalla, Juliana Trindade Clemente-Napimoga, Alexandre Barboza de Lemos, Marcelo Henrique Napimoga

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Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bruno Dos Santos PaveiFaculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Rua José Rocha Junqueira, 13 - Swift, Campinas, SP, 13405-755, Brazil.
André Antonio PelegrineFaculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Rua José Rocha Junqueira, 13 - Swift, Campinas, SP, 13405-755, Brazil.
Henrique Ballassini AbdallaFaculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Rua José Rocha Junqueira, 13 - Swift, Campinas, SP, 13405-755, Brazil.
Juliana Trindade Clemente-NapimogaFaculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Rua José Rocha Junqueira, 13 - Swift, Campinas, SP, 13405-755, Brazil.
Alexandre Barboza de LemosFaculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Rua José Rocha Junqueira, 13 - Swift, Campinas, SP, 13405-755, Brazil.
Marcelo Henrique NapimogaFaculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Rua José Rocha Junqueira, 13 - Swift, Campinas, SP, 13405-755, Brazil. marcelo.napimoga@slmandic.edu.br.ORCID http://orcid.org/0000-0003-4472-365X

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 303123/2022-2Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

The aim of this study was to evaluate the effects of UV photofunctionalization on cellular behavior and implant stability using in vitro assays and clinical trial. For that, in vitro tests were performed on smooth titanium disks (machined only) and on disks treated with sandblasted acid-etched (SA) (irradiated or not with UV light for 30 min) to evaluate wettability, roughness, cytotoxicity, cell proliferation, adhesion, and type I collagen production. Subsequently, a clinical study was conducted, in which ten patients were randomly assigned to receive implants that were sandblasted acid-etched and irradiated with UV light (pre-treated for 5 min) on one side, and non-irradiated implants on the contralateral side. Implant stability was assessed biweekly using the Osstell device (ISQ values) up to the 14th week. Here, our data revealed that contact angle analyses showed that (SA) exhibited the highest contact angle among all groups (p < 0.05), whereas UV irradiation significantly decreased it (p < 0.05). The combination of (SA) and UV irradiation exhibited the greatest surface roughness (p < 0.05). Cell viability did not show any significant differences at any time point (p > 0.05), while cell proliferation was significantly increased in the (SA) and UV-irradiated group at 48 h (p < 0.05). Type I collagen levels did not differ statistically among the groups. In the clinical study, UV-irradiated implants demonstrated greater stability at measurement intervals 3, 4, and 6 (p < 0.05). In vitro UV irradiation improved wettability and surface roughness properties without affecting cellular activity. Clinically, the use of UV light resulted in superior implant stability.

Indexed as

Dental implantsImplant stabilityOsseointegrationPhotofunctionalizationTitanium dioxideUltraviolet light

Identifiers

PMID41920403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.