ArticleAntonie van Leeuwenhoek2026
Differential roles of Scj1 and Djp1, two DnaJ homologs, in virulence, cell wall integrity, and multi-stress tolerance of Beauveria bassiana.
Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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5 authors.
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Abstract
Enhancing environmental adaptability and virulence is crucial for improving the biocontrol potential of Beauveria bassiana, a filamentous entomopathogen widely employed for biological pest control in agriculture and forestry. It was reported that DnaJ proteins play important and distinct roles in fungal growth, conidiation, environmental adaptation, and virulence. However, apart from Mas5 and Mdj1, the functions of other DnaJ proteins in B. bassiana remain largely unexplored. In this study, the functions of two DnaJ homologs of Scj1 and Djp1 in B. bassiana were characterized through multi-phenotype analyses under normal and stressful conditions. Deletion of scj1 or djp1 led to significant yet distinct changes in fungal growth, hyphal and conidial thermotolerance, nutrient utilization, cell wall integrity, antioxidant capacity, and tolerance to the fungicide carbendazim and UV-B radiation. Moreover, Δscj1 exhibited delayed conidial germination under normal condition, while Δdjp1 showed reduced fungal sensitivity to NaCl. Furthermore, the median lethal time (LT
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