ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2026
[Specialized geriatric care in intensive care units: from frailty to functional prognosis].
Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntensive care units (ICUs) increasingly treat very old adults with multimorbidity, frailty, and high medication burden. Chronological age alone is a poor proxy for benefit and prognosis; premorbid function, vulnerability (frailty), and cognitive reserve are pivotal. European cohorts of ICU patients aged ≥ 80 years show a high prevalence of frailty (Clinical Frailty Scale [CFS] ≥ 5 around 43%) and an independent association with 30-day mortality (e.g., hazard ratio [HR] ~1.5 in very old ICU patients [VIP] 1). VIP2 confirmed the prognostic contribution of CFS after adjustment including Sequential Organ Failure Assessment (SOFA) and admission diagnoses. Evidence syntheses and implementation reports suggest that structured bundles (ABCDEF) can improve delirium-related and functional outcomes.
methodsWe propose a geriatric ICU bundle integrating frailty assessment, structured goals-of-care (including time-limited trials), delirium prevention, light sedation, early mobilization, protein-adapted nutrition, medication safety, and deprescribing at ICU discharge.
conclusionGeriatric critical care represents a paradigm shift from isolated physiological stabilization towards trajectory-based treatment with explicit functional goals. Systematic vulnerability assessment, evidence-based bundles, and time-limited trials may reduce both overtreatment and undertreatment and improve the likelihood of meaningful recovery.
Indexed as
Identifiers
41920214What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.