ReviewCritical care science2026
Optimal nutritional support is key to liberation from mechanical ventilation.
Review in Critical care science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liberation from mechanical ventilation is a physiologically demanding phase of critical illness that requires coordinated recovery of respiratory muscle function, metabolic stability, and systemic resilience. Nutritional therapy plays a central role in supporting this transition. However, early aggressive caloric and protein delivery has not improved outcomes and may be detrimental. Current evidence supports a phase-adapted, individualized approach: permissive underfeeding during acute inflammation, moderate protein provision, monitoring of metabolic tolerance, and targeted correction of micronutrient deficiencies. Future research should incorporate time to successful weaning as a clinically meaningful endpoint when evaluating nutritional interventions in the intensive care unit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.