Evidence map›Paper›PMID 41919805›Full record

ArticleArquivos brasileiros de cardiologia2026

Predictive Value of the Systemic Immune-inflammation Index for Recurrence of Idiopathic Acute Pericarditis.

Tuba Unkun, Busra Guvendi Sengor

Abstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Tuba UnkunDepartment of cardiology, Kartal Kosuyolu Education and Research Hospital, Istanbul - Turquia.ORCID 0000-0003-0737-6927
Busra Guvendi SengorDepartment of cardiology, Kartal Kosuyolu Education and Research Hospital, Istanbul - Turquia.ORCID 0000-0001-7946-1229

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentifying patients at increased risk of recurrence of acute pericarditis remains challenging. High-sensitivity C-reactive protein (hs-CRP) can be used to predict recurrence, but it has certain limitations.

objectivesThis study aimed to evaluate the association between a novel biomarker, the Systemic Immune-Inflammation Index (SII), and the recurrence of acute pericarditis.

methodsThis retrospective cohort study included 110 patients diagnosed with acute idiopathic pericarditis, the primary endpoint of the study was to investigate Recurrent Pericarditis (RP) during the 18 month follow-up period. Patients were divided into two groups based on whether or not they developed recurrent pericarditis. Physical examination, electrocardiography, echocardiography, and laboratory test results of these patients were evaluated. P < 0.05 was considered statistically significant.

resultsThe mean age of the patients was 42.8 ± 15.2 years, and 42.7% were male. The group with RP had significantly higher leukocyte counts (8.7 ± 3.2 vs. 12 ± 4.7; p = 0.001), neutrophil counts (5.4 ± 2.7 vs. 9 ± 4.5; p < 0.001), hs-CRP levels (29.1 ± 40.9 vs. 49.5 ± 62.2; p = 0.048), and neutrophil-to-lymphocyte ratio (2.9 ± 2.5 vs. 6 ± 2.8; p < 0.001). SII (783.2 ± 770.2 vs. 1664.2 ± 1086.6; p < 0.001) was also significantly higher in patients with recurrence. Both SII and hs-CRP were independently associated with recurrence (p < 0.001 and p < 0.05, respectively).

conclusionSII and hs-CRP were found to be independent predictors for recurrence in acute pericarditis patients during the 18 month follow-up. Similar to hs-CRP, SII may also be used as an important parameter in predicting recurrent pericarditis.

Indexed as

C-Reactive ProteinPericarditisAcute DiseaseAdultBiomarkersFemaleHumansInflammationLeukocyte CountMaleMiddle AgedPredictive Value of TestsRecurrenceRetrospective StudiesBiomarkersC-Reactive Protein

Identifiers

PMID41919805
PMCPMC13128187

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