Evidence map›Paper›PMID 41919680›Full record

SynthesisPain research & management2026

Comparison of the Effects of Three Types of Exercise (Aerobic Exercise, Resistance Training, and Mind-Body Exercise) on Fibromyalgia: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.

Yikang Pan, Kaihong Sun, Jianfeng Chen, Zhiyong Wu

Abstract readSystematic ReviewNetwork Meta-AnalysisComparative Study
In one paragraph

Synthesis in Pain research & management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yikang PanSports Department, Changzhou Vocational Institute of Textile and Garment, Changzhou, 213164, China.ORCID https://orcid.org/0009-0009-5170-3535
Kaihong SunSports Department, Changzhou Vocational Institute of Textile and Garment, Changzhou, 213164, China.
Jianfeng ChenSports Department, Changzhou Vocational Institute of Textile and Garment, Changzhou, 213164, China.
Zhiyong WuSports Department, Changzhou Vocational Institute of Textile and Garment, Changzhou, 213164, China.ORCID https://orcid.org/0009-0007-1394-7374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew studies have compared the effects of different types of exercise on the management of patients with fibromyalgia. Therefore, we conducted this systematic review with meta-analysis to evaluate the effects of three types of exercise on the treatment of fibromyalgia.

methodsSearch databases including PubMed, Cochrane, Embase, and Web of Science from their inception to October 15, 2022, for randomized controlled trials (RCTs) investigating the effects of exercise on people with fibromyalgia.

resultsA systematic analysis was conducted on 21 RCTs involving 1638 participants and five distinct interventions. Most participants were female, consistent with the epidemiological characteristics of fibromyalgia syndrome. Compared with routine healthcare, the results of FIQ showed that more significant relief of fatigue was associated with the combination of aerobic and mind-body exercises (SMD = -0.58 [95% CI: -1.14∼-0.01]), aerobic exercise (SMD = 0.79 [95% CI: 0.25∼1.33]), and mind-body exercise (SMD = 0.68 [95% CI: 1.05∼-0.32]). VAS results revealed that significant improvement in pain was associated with the combination of aerobic and mind-body exercises (SMD = -0.78 [95% CI: -1.54∼-0.02]), resistance training (SMD = -1.58 [95% CI: -2.67∼-0.49]), and mind-body exercise (SMD = -1.62 [95% CI: -2.35∼-0.90]). Analysis of the 6MWT results showed that patients to whom the mind-body exercise was delivered can walk farther (SMD = 33.03 [95% CI: 13.73∼52.34]), compared with those in the control group. A significant effect on 6-minute walk test (6MWT) performance was observed following aerobic exercise (SMD = -23.19 [95% CI: -38.78 to -7.60]); in contrast, no significant changes were found in the group that underwent combined aerobic and resistance exercise.

conclusionsThis systematic review shows the effects of single or mixed exercise intervention for the management of fibromyalgia and suggests appropriate exercise as a highly effective nonpharmacological therapeutic strategy.

Indexed as

ExerciseExercise TherapyFibromyalgiaMind-Body TherapiesResistance TrainingFemaleHumansRandomized Controlled Trials as Topicaerobic exercisefibromyalgiamind-body exercisenetwork meta-analysisresistance training

Identifiers

PMID41919680
PMCPMC13042347

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.