Evidence map›Paper›PMID 41919259›Full record

ArticleFrontiers in oncology2026

Automated detection of primary soft tissue sarcomas of the extremities using artificial intelligence and ChatGPT.

Hendrik Voigtländer, Fabian Schmitz, Dimitrios Strauss, Hans-Ulrich Kauczor, Sebastian Voigtländer, Svea Sauerwein, Sam Sedaghat

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hendrik VoigtländerDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Fabian SchmitzDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Dimitrios StraussDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Hans-Ulrich KauczorDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Sebastian VoigtländerDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Svea SauerweinCarl von Ossietzky Universität Oldenburg, Department of Computer Science, Oldenburg, Germany.
Sam SedaghatDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Developing effective Convolutional Neural Networks (CNN) for soft tissue sarcoma detection often requires numerous iterations and adjustments, demanding specialized IT (Information Technology) skills. This study aims to use ChatGPT 4 to simplify CNN adaptation, reducing the need for specialized IT skills while enabling efficient exploration of training configurations to enhance diagnostic accuracy. Methods: This study leveraged a preexisting Artificial Intelligence (AI) model adapted using a preexisting Convolutional Neural Network (CNN). The study involved 54 participants diagnosed with primary soft tissue sarcomas in the extremities and possessing complete Magnetic Resonance Imaging (MRI) datasets. AI adaptations and programming were conducted using TensorFlow and verified with ChatGPT. Model training involved a dataset split of 70% training, 15% validation and 15% test set on patient level split, processed over eight epochs. Results: The adapted CNN model demonstrated significant improvement across various MRI sequences, achieving high accuracy levels (up to 98.5%) and excellent sensitivity and specificity rates. The model performed robustly in differentiating tumor presence in MR images, with test accuracies as high as 93.9%. The inclusion of a Gradient-weighted Class Activation Mapping (Grad-CAM) heat map and probability scores in the diagnostic outputs further enhanced interpretative capabilities. Conclusion: This study highlights the potential of AI, particularly CNNs, in the early and accurate detection of soft tissue sarcomas, underscoring the technology's adaptability across different imaging modalities. The integration of large language models like ChatGPT into the model adaptation process emphasizes the reduced need for specialized IT skills, making advanced diagnostic tools more accessible and potentially improving diagnostic accuracy and patient outcomes in radiology and oncology.

Indexed as

artificial intelligenceChatGPTconvolutional neural networkMRIsoft-tissue sarcoma

Identifiers

PMID41919259
PMCPMC13033578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.