ArticleFrontiers in medicine2026
Pulmonary sarcoidosis with pleural involvement in a 44-year-old patient: a case report.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Although sarcoidosis is a granulomatous disease with unknown etiology involving multisystems, the pleura is rarely affected in this disease. Here, a case of sarcoidosis with pleural nodules and pleural effusion was presented. The patient suffered from dry cough and dyspnea lasting for 4 weeks. Chest computed tomography showed pulmonary nodules, subpleural nodules, mediastinal lymphadenopathy and bilateral pleural effusion. Thoracoscopic pleural biopsy was performed, and histopathological examination demonstrated non-caseating granulomas, confirming sarcoidosis-related pleural involvement. The patient was treated with corticosteroids, and all discomfort symptoms gradually regressed. A follow-up CT performed 8 weeks later exhibited the complete resolution of pleural effusion. The present case report highlights that when pleural effusion and pleural nodule are observed in a patient, sarcoidosis should be considered as the underlying disease while other potential causes are ruled out.
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