Evidence map›Paper›PMID 41919107›Full record

ArticleFrontiers in psychology2026

The mediating effect of emotion dysregulation on the relationship between childhood maltreatment and suicidal ideation in patients with depression.

Lina Chen, Yuling Feng, Yong Wang, Nana Xiong, Lixia Li, Xia Li

Abstract read
In one paragraph

Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Lina ChenSchool of Medicine, Jiangsu University, Zhenjiang, China.
Yuling FengIntravenous Infusion Therapy Center, Zhenjiang First People's Hospital, Zhenjiang, China.
Yong WangPeking University Sixth Hospital, Beijing, China.
Nana XiongPeking University Sixth Hospital, Beijing, China.
Lixia LiPeking University Sixth Hospital, Beijing, China.
Xia LiPeking University Sixth Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Childhood maltreatment is a well-established risk factor for suicidal ideation in patients with depression. However, the psychological mechanisms linking early adversity to current suicide risk remain incompletely understood. Early traumatic experiences may impair emotion regulation capacities, thereby exacerbating suicidal ideation. Objective: This study aimed to clarify the association between childhood maltreatment and suicidal ideation in depression by examining the potential mediating role of emotion regulation difficulties. Methods: We recruited 595 inpatients meeting ICD-10 criteria for a depressive episode. Participants underwent a comprehensive assessment, including sociodemographic and clinical data collection. Childhood maltreatment, suicidal ideation, and emotion regulation difficulties were evaluated using the Childhood Trauma Questionnaire (CTQ), the Beck Scale for Suicide Ideation-Chinese Version (BSI-CV), and the Difficulties in Emotion Regulation Scale (DERS), respectively. Pearson correlation analysis was used to examine associations among childhood maltreatment, difficulties in emotion regulation, and suicidal ideation. Structural equation modeling (SEM) and the bootstrap method were used to test the mediating effect, and the model was modified transparently according to modification indices. Results: Childhood maltreatment was significantly associated with higher levels of suicidal ideation in patients with depression. Furthermore, greater difficulties in emotion regulation were linked to increased suicidal ideation. Critically, mediation analysis indicated that emotion regulation difficulties partially mediated the relationship between childhood maltreatment and suicidal ideation. Conclusion: These findings suggest that childhood maltreatment exerts both a direct effect on suicidal ideation in patients with depression and an indirect effect through the exacerbation of difficulties in emotion regulation.

Indexed as

childhood maltreatmentdepressionemotion dysregulationmediating effectsuicidal ideation

Identifiers

PMID41919107
PMCPMC13033768

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.