SynthesisFrontiers in nutrition2026
Metabolic and bariatric surgery and male endocrine and reproductive health: a GRADE-assessed meta-analysis.
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- GLP-1 Receptor Agonists and Tirzepatide in Men Seeking Fertility: A Structured Narrative Review and Proposed Clinical Framework.Journal of clinical medicine · 2026Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The negative impact of obesity on male fertility and sexual health is well-established. Although metabolic and bariatric surgery (MBS) offers a powerful solution for severe obesity, its impact on the male androgens, semen quality, and sexual function are not yet fully understood. Methods: A comprehensive systematic search of the literature was conducted in PubMed, Embase, the Cochrane Library, and Web of Science for relevant studies published up to July 2024. Data about reproductive hormones, semen parameters, and sexual function in men with obesity undergoing bariatric surgery was extracted. For data synthesis, weighted mean differences (WMDs) and their 95% confidence intervals (CIs) were calculated using random- or fixed-effects models, as appropriate. Results: Fifty-nine studies with 60 arms were included in our meta-analysis. Metabolic and bariatric surgery indicated elevated levels of total testosterone (TT) (WMD: 5.46 nmol/L, Conclusion: Overally, this meta-analysis illustrated that bariatric surgery improves the hormonal profile and sexual function in obese men profoundly. These findings introduce bariatric surgery as an effective therapeutic strategy for weight loss management and male reproductive health improvement.
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