SynthesisFrontiers in nutrition2026
Assessing the impact of Spirulina supplementation on the growth of children and adolescents: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Background: Spirulina, a nutrient-dense blue-green microalgae, has been proposed as a sustainable intervention to combat undernutrition in children and adolescents. Despite its nutritional benefits, evidence regarding its impact on overall growth in this population remains limited and inconsistent. This systematic review and meta-analysis synthesizes the available evidence on impact of Spirulina supplementation on the growth of children and adolescents. Methods: Following PRISMA (version 2020) guidelines, we systematically searched five databases [PubMed, Embase, CINAHL, CENTRAL and Google Scholar (till 16 Findings: Of 208 identified studies, 5 met the inclusion criteria, and 2 were included in the meta-analysis. The pooled SMD for weight changes was -0.526 (95% CI, -1.289 to 0.236), indicating no statistically significant effect ( Interpretation: Spirulina supplementation did not show a statistically significant impact on growth outcomes in children and adolescents. Further high-quality studies are needed to explain its role as a nutritional intervention. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO, identifier: CRD4202457183.
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