Evidence map›Paper›PMID 41918964›Full record

Article... International Conference on Learning Representations2025

Learning General-Purpose Biomedical Volume Representations using Randomized Synthesis.

Neel Dey, Benjamin Billot, Hallee E Wong, Clinton J Wang, Mengwei Ren, P Ellen Grant, Adrian V Dalca, Polina Golland

Abstract read
In one paragraph

Article in ... International Conference on Learning Representations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Robust Fetal Pose Estimation across Gestational Ages via Cross-Population Augmentation.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
    Article
  4. PolyPose: Deformable 2D/3D Registration via Polyrigid Transformations.Advances in neural information processing systems · 2025
    Article
  5. Article
  6. Deep infant brain segmentation from multi-contrast MRI.Conference record. Asilomar Conference on Signals, Systems & Computers · 2025
    Article
  7. Article
  8. MultiMorph: On-demand Atlas Construction.Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition · 2025
    Article
  9. Unraveling Normal Anatomy via Fluid-Driven Anomaly Randomization.Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Neel DeyMIT CSAIL.
Benjamin BillotMIT CSAIL.
Hallee E WongMIT CSAIL.
Clinton J WangMIT CSAIL.
Mengwei RenNew York University.
P Ellen GrantHarvard Medical School.
Adrian V DalcaMIT CSAIL.
Polina GollandMIT CSAIL.

Funding

Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
Fetal MRI: robust self-driving brain acquisition and body movement quantificationR01EB032708 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2022 to 2025
$2.8M
Developing novel MR tools to optimize surgical planning and fetal outcome in TTTSR01HD114338 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ELFAR ADALSTEINSSON, Patricia Ellen Grant · 2024 to 2026
$2.2M
Fast and Robust Deep Learning for Medical imaging: Segmentation and Registration methods invariant to contrast and resolutionR01EB033773 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Adrian Dalca · 2023 to 2026
$2.2M
NIBIB NIH HHS R01 EB032708NIBIB NIH HHS R01 EB033773NICHD NIH HHS R01 HD100009NICHD NIH HHS R01 HD114338
6 · The paper itself

Abstract

Current volumetric biomedical foundation models struggle to generalize as public 3D datasets are small and do not cover the broad diversity of medical procedures, conditions, anatomical regions, and imaging protocols. We address this by creating a representation learning method that instead anticipates strong domain shifts at training time itself. We first propose a data engine that synthesizes highly variable training samples that would enable generalization to new biomedical contexts. To then train a single 3D network for any voxel-level task, we develop a contrastive learning method that pretrains the network to be stable against nuisance imaging variation simulated by the data engine, a key inductive bias for generalization. This network's features can be used as robust representations of input images for downstream tasks and its weights provide a strong,

Identifiers

PMID41918964
PMCPMC13035308

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.