Evidence map›Paper›PMID 41918938›Full record

ArticleFrontiers in surgery2026

Evaluation of microbiological cultures in patients with acute cholecystitis.

Dániel Váczi, Mária Matuz, Ria Benkő, Illés Tóth, Emil Terhes, Edit Hajdú, Erika Papfalvi, András Nagy, György Lázár, Szabolcs Ábrahám

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Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Dániel VácziDepartment of Surgery, University of Szeged, Szeged, Hungary.
Mária MatuzInstitute of Clinical Pharmacy, University of Szeged, Szeged, Hungary.
Ria BenkőInstitute of Clinical Pharmacy, University of Szeged, Szeged, Hungary.
Illés TóthDepartment of Surgery, University of Szeged, Szeged, Hungary.
Emil TerhesDepartment of Surgery, University of Szeged, Szeged, Hungary.
Edit HajdúInfectious Disease Ward, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Erika PapfalviInfectious Disease Ward, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
András NagyDepartment of Radiology, University of Szeged, Szeged, Hungary.
György LázárDepartment of Surgery, University of Szeged, Szeged, Hungary.
Szabolcs ÁbrahámDepartment of Surgery, University of Szeged, Szeged, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Acute cholecystitis (AC) requires emergency care. Besides surgical interventions, adequate empirical antibiotic therapy is indispensable. We aimed to analyze bile samples obtained during surgical interventions for AC. The primary aim was determine sampling frequency, pathogen prevalence (including ESKAPE strains), and to create the cumulative antibiogram of the most common bacteria (including MDR pathogens). A secondary aim was to explore the potential relationship between pathogen type (ESKAPE, MDR) and different patient characteristics in acute cholecystitis. Methods: A retrospective observational study was conducted. Bile samples from patients undergoing acute cholecystectomy or percutaneous transhepatic gallbladder drainage for acute cholecystitis between 2005 and 2019 were analyzed. Cases were retrieved based on the respective ICD-10 codes. Descriptive and univariate methods were used. Results: During the study period there were 656 patients with AC; bile samples for microbiology were collected in 379 cases (57.8%). Overall, 412 bacteria, predominantly Gram-negative microbes (60.9%), were isolated. The most common bacteria included Conclusion: Microbiological sampling, identifying the most common pathogens and determining the antibiotic resistance profile in AC is important to determine the optimal empirical antibiotic choice.

Indexed as

acute cholecystitisanti-bacterial agentsbacterialbilecholecystectomydrug resistancemicrobiology

Identifiers

PMID41918938
PMCPMC13033935

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