Evidence map›Paper›PMID 41918715›Full record

ArticleNeuro-oncology advances

Increased cortical excitability to transcranial magnetic stimulation at the brain-tumor interface of

Alexia Stark, Mykola Gorbachuk, Kathrin Machetanz, Maria Teresa Leao, Marina Liebsch, Sophie Wang, Jürgen Honegger, Marcos Tatagiba, Georgios Naros

Abstract read
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Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexia StarkNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Mykola GorbachukNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Kathrin MachetanzNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Maria Teresa LeaoNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Marina LiebschNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Sophie WangNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Jürgen HoneggerNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Marcos TatagibaNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.ORCID https://orcid.org/0000-0002-1627-9937
Georgios NarosNeurosurgical Clinic, Department of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.ORCID https://orcid.org/0000-0003-4807-6234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is increasing interest in the glioma-to-neuro communication at the brain-tumor interface (BTI). In vitro studies indicate that gliomas with a mutation of the isocitrate dehydrogenase ( Methods: To investigate peritumoral cortical excitability (CE), we applied 5258 pulses of transcranial magnetic stimulation (TMS) at the BTI of Results: Within our sample, there was no significant group difference in RMT. The TMS to the BTI triggered an EMG synchronization decreasing linearly with the distance to the functional hotspot. In contrast, Conclusions: This study provides in vivo evidence of cortical hyperexcitability at the BTI of

Indexed as

brain-tumor interfaceepileptogenesisgliomaisocitrate dehydrogenasetranscranial magnetic stimulation

Identifiers

PMID41918715
PMCPMC13035068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.