ArticleIndian journal of endocrinology and metabolism
Vitamin D Status and Calcium Homeostasis in Mother and Newborn Dyad: A Hospital Based Study from South Delhi.
Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Studies in the 2000s in India showed a high prevalence of vitamin D deficiency in apparently healthy pregnant women and their newborns. With awareness about sunshine exposure and vitamin D supplementation, vitamin D deficiency would have declined over the last two decades. We assessed current vitamin D status of maternal-newborn dyads at a teaching institute in Delhi. Methods: The study included 104 pregnant women (27.8 ± 4.2 yrs) and their singleton healthy term newborns (M: F = 63:41) delivered at HIMSR Delhi during years 2023-25. Cord-blood was drawn at delivery, and fasting maternal blood was drawn for serum total calcium, phosphate, alkaline phosphatase, 25(OH)D, and intact-PTH assessment. Serum 25(OH)D and PTH were measured by chemiluminescence assay. Results: The median (IQR) serum 25(OH)D of mothers and newborns was 11.8 (6.9-19.1) and 13.7 (7.9-24.7) ng/mL, respectively. Serum 25(OH) was <12 ng/mL in 51% of mothers and 44% of newborns. Maternal and cord-blood 25(OH)D correlated significantly ( Conclusion: A high prevalence of vitamin D deficiency in mothers and newborns was observed, despite two decades of awareness. This emphasizes for more targeted and proactive public health initiatives to combat maternal and neonatal hypovitaminosis D.
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